Immunity Cells Prevents Metastatic Tumors by Attack on Tumor Vaccination
Vasculature with Both Cellular and Humoral Immunity
Cells Prevents Metastatic Tumors by Attack on Tumor
Vaccination
Journal of Experimental & Clinical Cancer Research
Inhibition of B16 melanoma growth and metastasis in C57BL mice
by vaccination with a syngeneic endothelial cell line
Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine
The breaking of immune tolerance against autologous angiogenic endothelial cells should be a
useful approach for cancer therapy. Here we show that immunotherapy of tumors using fixed
xenogeneic whole endothelial cells as a vaccine was effective
Vaccination with autologous endothelium inhibits angiogenesis and metastasis of colon cancer through autoimmunity
Overcoming immune tolerance of tumor angiogenesis should be
useful for adjuvant therapy of cancer. We hypothesized that vac-
cination with autologous endothelium would induce an autoim-
mune response
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma
We aimed to assess the clinical efficacy of glutaraldehyde-fixed
human umbilical vein endothelial cell (HUVEC) vaccine for the
treatment of patients with recurrent glioblastoma.
Pilot study of anti-angiogenic vaccine using fixed whole endothelium in patients with progressive malignancy after failure of conventional therapy
Angiogenesis, the growth of new blood vessels, is essential for
tumour growth and metastasis.1–5 Whereas angiogenesis oc-
curs minimally in normal adult tissues, it is intensive in
developing tumours,
