Immunity Cells Prevents Metastatic Tumors by Attack on Tumor Vaccination

Vasculature with Both Cellular and Humoral Immunity
Cells Prevents Metastatic Tumors by Attack on Tumor
Vaccination

Journal of Experimental & Clinical Cancer Research

Inhibition of B16 melanoma growth and metastasis in C57BL mice
by vaccination with a syngeneic endothelial cell line

Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine

The breaking of immune tolerance against autologous angiogenic endothelial cells should be a
useful approach for cancer therapy. Here we show that immunotherapy of tumors using fixed
xenogeneic whole endothelial cells as a vaccine was effective

Vaccination with autologous endothelium inhibits angiogenesis and metastasis of colon cancer through autoimmunity

Overcoming immune tolerance of tumor angiogenesis should be

useful for adjuvant therapy of cancer. We hypothesized that vac-
cination with autologous endothelium would induce an autoim-
mune response

Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma

We aimed to assess the clinical efficacy of glutaraldehyde-fixed
human umbilical vein endothelial cell (HUVEC) vaccine for the
treatment of patients with recurrent glioblastoma.

Pilot study of anti-angiogenic vaccine using fixed whole endothelium in patients with progressive malignancy after failure of conventional therapy

Angiogenesis, the growth of new blood vessels, is essential for
tumour growth and metastasis.1–5 Whereas angiogenesis oc-
curs minimally in normal adult tissues, it is intensive in
developing tumours,